$165M Series B / Scalable GTM Engine
We rebuilt Karius’ GTM engine, reducing costs by 60% and driving 248% more SQLs with smart, scalable systems.
Client:
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Kariusdx.com
Category:
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Complete Marketing Tech Stack Build
The Challenge
Karius’ groundbreaking microbial cell-free DNA test needed a straightforward, compelling story—and a digital engine to tell it. An aging website, a lack of unified marketing technology (mar-tech) stack, high agency spend, and low brand recognition left healthcare professionals uncertain about the product’s value.
The Solution
We rebuilt Karius’ go-to-market foundation:
Website re-architecture (TAM-driven) that translated complex genomics into pitch-deck-style visuals clinicians could grasp.
In-house tech stack—BigQuery data warehouse, integrated CRM/CMS, and marketing automation—to cut external costs and surface real-time insights.
AI/ML-powered targeting (IQVIA, Lasso) for personalized email, site personalization, and programmatic ads.
SEO + data-driven content to rank for high-intent clinical queries and double aided / unaided awareness.
The Result
248% YoY jump in SQLs (244 vs 70 target).
7.7 million impressions and 71% engagement.
160% lift in top-10 Google keywords and
75% boost in product usage, all from a platform Karius still runs today.
